ABSTRACT
Data results for pre-COVID era vs COVID-era Pre-COVID-era (n=234) COVID-era (n=296) P value Age 58.6 ± 12.2 55.0±13.7 0.001 Male Gender 103 135 0.72 Latin Ethnicity 7 10 0.92 qSOFA total 1.84 ± 0.60 2.43±0.68 < 0.0001 qSOFA respiration 0.12±0.33 0.81±0.39 <0.0001 qSOFA blood pressure 0.93±0.25 0.87±0.34 0.02 qSOFA brain 0.79±0.41 0.75±0.43 0.33 WBC 10.9±7.6 12.5±8.2 0.02 MELD-Na 23.8±10.1 26.0±10.2 0.01 Reason for ICU: Altered Mental Status 117 141 0.59 Infection 115 138 0.56 CVA 12 13 0.69 Hypotension 134 153 0.20 Renal Support 35 88 <0.0001 Respiratory Failure 115 129 0.20 Post-procedure 16 27 0.34 Type of Infection: Nosocomial infection 24 10 <0.001 UTI 11 27 0.05 Abdominal 31 32 0.39 Bacteremia 32 28 0.13 Respiratory 48 57 0.72 Skin/Soft Tissue 10 7 0.22 Organism details: Gram positive 39 36 0.14 Gram negative 31 25 0.08 Fungus 10 12 0.90 > 1 organism 11 5 0.04 VRE 6 5 0.49 MRSA 7 2 0.04 Fluoro resistance 5 2 0.14 ESBL 11 5 0.04 Outcome: ICU length of stay 4.78±4.34 7.66±8.58 <0.0001 Renal Failure 35 83 <0.0001 Grade 3-4 Hepatic Encephalopathy 55 98 0.02 Shock 78 121 0.08 Ventilation 82 115 0.37 Coagulation failure 144 175 0.57 Death or hospice 82 119 0.22 Liver Transplant 6 31 0.001 Key: quick sepsis-related organ failure assessment (qSOFA);white blood cells (WBC);Model for end-stage liver disease-sodium (MELD-Na);intensive care unit (ICU);cerebrovascular accident (CVA);urinary tract infection (UTI);vancomycin resistant enterococcus (VRE);methicillin resistant staphylococcus aureus (MRSA);fluoro (fluroquinolone);extended spectrum beta-lactamase (ESBL).